BIOGAMI Frequently Asked Questions (FAQs)

To help provide timely information about all aspects of the program, this page is updated periodically in response to questions from potential performers.  

Full information about BIOGAMI and the application process is in the solicitation on SAM.gov. Ask questions via the ARPA-H Solutions Portal linked below. Please note, you will first need to sign-in or register an account to submit a question.

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Technical Questions

No. One-on-one discussions between potential proposers and the BIOGAMI team should be requested as sidebars during Proposers' Day.

Correct, BIOGAMI requires two indications. The indications may be one rare NDD and one non-rare, non-NDD, or one non-rare NDD and one rare non-NDD.

BIOGAMI is not prescriptive towards a breadth vs depth approach. Proposers should describe their methods and justify their choice towards achieving the end goal of a highly accurate computational tool that can be applied to any intrinsically disordered protein.

Team and Submission Eligibility

No, there is no maximum team size for BIOGAMI submissions. Teams should have the expertise and capacity to achieve the goals of the proposed work.

Yes, individuals may participate on more than one team and be listed on multiple submissions. There is no restriction on being part of multiple teams. 

The consortium agreement does not need to be signed prior to proposal submission, but it should be formalized by the time of award.

Section 2.8 of the BIOGAMI ISO describes the requirements for a multi-party teaming arrangement structure. The multi-party team generally chooses one member to act as the agent and/or lead member for administration and reporting purposes. There is no preference for the lead member to be a for-profit company or a research institution.

Section 2.8 of the BIOGAMI ISO describes the requirements for a multi-party teaming arrangement structure, which is distinct from the traditional NIH model. In this structure, leadership can change among team members based on expertise and project phase. The multi-party team generally chooses one member to act as the agent and/or lead member for administration and reporting purposes, but this agent does not need to be the lead performing organization. The ISO does not prescribe specific titles (such as Executive Director, Scientific Director, and Principal Investigator) for team leadership. Instead, proposals should clearly describe the anticipated leadership structure and changes throughout the program. The key is to demonstrate a flexible, dynamic team structure that meets the program’s requirements.

Proposers’ Day Specifics

  • The Proposers’ Day will be held from 9:00 AM to 5:00 PM Eastern Time on February 20, 2026.  
  • Doors open and webinar login begins for registered attendees at 8:30AM.  
  • A final agenda, including order of Lightning Talks and Sidebars, will be emailed to registered attendees before the meeting.

No. Lightning talks can be presented either in person or virtually, but Proposer’s Day does not offer an option to play prerecorded videos.

The BIOGAMI audience will include ARPA-H staff and contractors, other US Government employees, and the potential performer community – including individuals from academia and industry. 

BIOGAMI Proposers' Day is a hybrid event with both virtual and in-person attendance options. A recording of Proposers' Day will be posted to the BIOGAMI website a few days following Proposers' Day.

No. One-on-one discussions between potential proposers and the BIOGAMI team should be requested as sidebars during Proposers' Day.

No, all the required information for Proposers' Day is requested within the registration portal.

Yes. Virtual attendees may present their Lightning Talk through the webinar, or they may delegate to an in-person attendee from their team.

Yes. Sidebars for virtual attendees will be scheduled for the following Monday, February 23rd.

Dates & Deadlines

The BIOGAMI Solution Summary submission deadline is fixed. You may submit a Solution Summary even if your SAM.gov registration is not yet complete.